What to Expect

The Key to Control…

Stimate^® Nasal Spray is the key to safe, effective first-line treatment of mild-to-moderate type 1 von Willebrand disease (VWD). It is the first and only high-concentration desmopressin acetate nasal spray that triggers your body’s natural ability to release von Willebrand factor (VWF), enabling your blood to clot.

Stimate^® Nasal Spray is effective in controlling bleeding and is proven to work in patients with
type 1 VWD. (It is usually not effective for patients with the severe form of type 1, or in other VWD types.)

...and Convenience

Stimate^® Nasal Spray is a VWD treatment designed for patients with on-the-go lifestyles. Stimate^® Nasal Spray is a convenient nasal spray that offers you greater control over your VWD and your life. It gives you an easy, reliable, and discreet way to treat minor bleeding episodes. Because you can administer your own treatment, you may not have to go to the doctor’s office or emergency room as often.

Learn about Stimate^® Nasal Spray results.

Important Safety Information

Stimate^® Nasal Spray is indicated for patients with mild to moderate classic type 1 von Willebrand disease (VWD) with Factor VIII levels greater than 5%. Stimate^® Nasal Spray is not indicated for the treatment of severe classic VWD (type 1) and when there is evidence of an abnormal molecular form of Factor VIII antigen.

Stimate^® Nasal Spray is contraindicated in individuals with a known hypersensitivity to desmopressin or any of the components of Stimate^®. Stimate^® should not be used in patients with type 2B VWD, since platelet aggregation may be induced. Stimate^® Nasal Spray is for intranasal use only.

To decrease the potential for hyponatremia or water intoxication, especially in the young and the elderly, patients using desmopressin who are not in need of antidiuretic hormone for its antidiuretic effect should be cautioned to reduce fluid intake, ingesting only enough to satisfy thirst. Such patients should be monitored for the rare occurrence of an extreme decrease in plasma osmolality that could result in seizures, possibly leading to coma.

Other adverse reactions reported with use of injectable and/or intranasal desmopressin acetate include headache, nausea, somnolence, dizziness, chest pain, palpitations and tachycardia, and severe allergic reactions, including anaphylaxis. See full prescribing information for a complete list of adverse reactions.